Main Topics

The IDMC-11 program will be structured around the following 8 topics:

Session 1: Microsatellite Instability and Epigenetics

This session covers all aspects of the mutations associated with DM, including population genetics, particularities of the mutations, epigenetic modifications and repeat instability mechanisms.

Session 2: Disease Mechanisms: DM1, DM2 and CDM

This session covers the research devoted to understanding DM disease mechanisms in various model systems, with the exception of repeat instability mechanisms covered in Session 1.

Session 3: Cancer and Aging in DM

This session covers preclinical and clinical studies of the underlying mechanisms and progression of cancer and premature aging in DM.

Session 4: Clinical, Ethical and Social Issues and Disease Burden

This session covers all clinical aspects of DM and its burden on patients and caregivers, as well as ethical and social issues in DM patients and families.

Session 5: Specific Disease FeaturesCNS, Cardiac, GI

This session covers organ-specific phenotypes of DM and practices for their management and treatment.

Session 6: Cell Models for DM

This session covers in vitro model systems, their development and use in mechanistic studies or therapy development.

Session 7: Animal Models and Tissue-specific Mechanisms

This session covers in vivo model systems, their development and use in mechanistic studies or therapy development.

Session 8: RNA Clinical Research MethodsBiomarkers, Outcome Measures, Registries, Trial Design and Therapeutics

This session covers clinical trial readiness resources and tools used in the clinical development of new therapeutic strategies.